Pioneering the Future of Eyecare
At Twenty Twenty, we envision a world where technology, pharmaceuticals, and devices come together to revolutionize the eyecare industry. As pioneers in this field, we’re dedicated to turning this dream into reality. Supported by more than 400 US and International patents, our groundbreaking devices will transform the way we approach eyecare – with the aspiration of making it more efficient and effective for everyone. With our recent acquisition of KaliCare, we are poised to make a meaningful difference in the lives of patients and those that care for them by combining connected therapeutics and personalized digital health interventions.
Professional
Services
Glaucoma
Precision Care
Dry Eye
Therapeutics
Smart Lenses
Horizon
Introducing the VS 2020
Self Guided Entrance Exams, Anywhere Anytime
The VS2020 is a virtual reality platform engineered to enhance patient engagement, reduce staff involvement, and deliver objective measurements.. With our unique self-guided technology, patients can independently complete seven common entrance tests from any location within your practice.
Test results are uploaded to a secure provider portal and can be evaluated from any device on your network. Embrace the future of eye care with the VS2020 platform!
7 Entrance Exams in one platform
Pupil response ● Eye motility ● Eye alignment, alternative cover test ● Eye alignment, unilateral cover/ uncover ● Color vision ● Contrast sensitivity ● Screening visual fields
TrueTrac gaze based navigation
The first Hands-free VR based testing experience. Helps standardize the exam process, while minimizing false click errors.
Dynamic Viewing / Reporting
Manage the testing process from any connected device on your network, With dynamic reporting, results can be analyzed for changes over time, giving you deeper insights into your patients’ eye health.
Kali Home
Transforming Glaucoma Management with At-Home Eye Pressure Monitoring
Infrequent IOP (intraocular pressure) measurements can limit glaucoma management, but Kali Home aims to change that.
This take-home device will enable patients to self-monitor their eye pressure, enhancing disease tracking and providing data for more personalized glaucoma care.
Kali Home* will offer:
- LED-based guidance assistance for effortless self-alignment
- Automatic measurement capture
- Bluetooth connectivity with our mobile app for trend analysis and seamless communication with the patient’s eye care professional
- Integrates into our Twenty/Twenty Vision Suite for comprehensive glaucoma management
Stay tuned for the Kali Home revolution in glaucoma management!
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Viscous Microdose Delivery
Simplifying Eye Drop Instillation
Applying eye drops correctly can be challenging due to aiming difficulties, blinking or flinching and dexterity issues
Our aim is to make eye drop application easier, while reducing waste. This innovative device automatically releases a microdose of the selected eye drop onto the ocular surface (not the eyelids) using a unique LED aiming technique, triggered right after the user blinks!
This product will come with interchangeable cartridges of ophthalmic eye drops, starting with lubricating artificial tears to help manage dry eye symptoms.
Key features will include:
- Horizontal eye drop delivery
- LED-guided aiming for precise drop placement
- Automatic blink delivery and a manual delivery option
- Connectivity with our mobile app for eye drop and symptom tracking, as well as adherence reminders
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Drug Dispensing Contact Lens
Simplifying Therapy Adherence for Glaucoma
Managing glaucoma can be challenging, especially when it comes to medication adherence at home.
Our solution is a programmable drug dispensing contact lens designed to improve compliance of vision-saving glaucoma medications.
- Controls timing and dose of drug delivery
- Improves medication compliance
- Reduces eye drop intolerance by minimizing dose
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Closed-loop Glaucoma Pump
Revolutionizing Glaucoma Treatment
Glaucoma drainage devices often fail in a significant number of patients, with nearly 50% of implants becoming ineffective after just one year.
Our device is a closed-loop glaucoma pump designed to revolutionize glaucoma treatment. It is the first active glaucoma drainage device that will dynamically regulate intraocular pressure for more consistent eye pressure management in patients with glaucoma.
Expected Benefits:
- Overcomes common reasons for failure of glaucoma drainage implants
- Dynamic IOP control in both the diurnal cycle and over time
- Anti-immunogenic material to reduce post-implantation fibrosis
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Kali Care
Kali Smart Dropper
Enhancing Eye Drop Adherence with Innovative Technology
Applying and tracking eye drop medication can be challenging, but the Kali Smart Dropper aims to change that. This smart eye dropper assistant will help boost adherence by reminding patients to take their drops, confirming they were applied correctly, and assisting with data collection and reporting.
The Kali Smart Dropper* will be a lightweight, portable,device designed to attach to an eye drop bottle. As a connected smart eye dropper, it will provide drop instillation assistance and real-time tracking of successful drop use.
Features of the Kali Smart Dropper* will include:
- Guidance feedback during drop application
- Detection of successful drop installation
- Adherence tracking and reminders via our mobile app
- Integrates into our Twenty/Twenty Vision Suite for comprehensive glaucoma management
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Meibomian Gland Dysfunction
Transforming MGD Therapy: Combining Heat and Massage in One Simple Solution
Dry eye caused by meibomian gland dysfunction (MGD) can be painful and costly to manage, with current treatments presenting various challenges.
At-home therapies like compress masks often fall short and require extra time and maintenance, while in-office procedures are expensive, complex, and lengthy.
Our solution will combine the typical in-office procedure into a single device, applying therapeutic levels of heat to the eyelids and delivering targeted massage to the entire lid in under 3 minutes, streamlining MGD treatment for patients.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Intravitreal Injection
Personalizing IVI therapy
Intravitreal injection (IVI) therapy is widely used for nvAMD and DR, but over 10% of patients don’t adquently respond and undergo multiple cycles before changing therapy, risking vision loss. Biomarkers could help physicians personalize treatment for individual patients.
Our advanced intravitreal injection technology allows for tissue sampling and therapeutic injection in one step, analyzing vitreous biomarkers to determine the best treatment options for macular degeneration patients.
Anticipated Benefits:
- Personalized therapy based on biomarkers
- Reduced risk of IVI complications
- Eliminates current “trial and error” approach for macular degeneration therapy
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Tonoptic
Continuous IOP Monitoring: A Breakthrough in Glaucoma Management
Eye pressure tends to be most elevated in the early morning when patients are asleep. These unmonitored early morning spikes can negatively affect glaucoma management. While home monitoring devices are helpful, their effectiveness depends on users taking the initiative to take a measurement.
Tonoptic is a minimally invasive, implantable device created to offer continuous eye pressure monitoring, enabling personalized and precise glaucoma management.
Utilizing advanced microelectronics, Tonoptic will feature an optically integrated MEMS pressure sensor and a handheld reader. The device will integrate with the Twenty/Twenty Vision Suite for comprehensive glaucoma management.
Tonoptic is set to revolutionize glaucoma care.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Aqueous Deficiency
Natural Dry Eye Relief
Dry-eye disease can be painful, expensive, and challenging to manage, significantly impacting patients’ quality of life and comfort.
Our innovative solution is an ocular wearable device, similar to a contact lens, but discreetly located in the inferior fornix (hidden by the lower eyelid). This unique device uses low-level electrical currents to stimulate natural tear production for those with dry eye, all while being encased in a comfortable hydrogel material.
- Natural, preservative free dry eye therapy
- Wireless, on-demand therapy initiation for all day relief
- Integrates into Twenty/Twenty Vision Suite for comprehensive dry eye management
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Neuroprotection
Fighting Blindness with Groundbreaking Neuroprotection Lenses
Retinitis Pigmentosa (RP) is a rare inherited disease that often results in blindness and currently, no definitive treatment is available.
Our Neuroprotection Lens offers hope by aiming to slow or halt retinal degeneration in RP patients and other neurodegenerative eye diseases through transcorneal stimulation.
This product will utilize transcorneal stimulation to reverse retinal degeneration in patients with RP and other degenerative eye diseases.
- Clinical data supports neuro-protective and vision enhancing efficacy
- Well-tolerated, non-invasive therapy
Tackling the challenges of degenerative eye disease with our revolutionary Neuroprotection Lens.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Myopia Wearables
Combating Myopia with Violet Light Technology
Myopia is a growing pandemic with highest rates in Asia. Current solutions are expensive, time consuming, increase risk of infection or have potential for side effects (Ortho-K, soft Multifocal contact lenses, Atropine).
Myopia wearable is a pair of compact optoelectronic components that can be semipermanently attached to a child’s glasses of choice to emit violet light that has been shown to slow myopia progression. The devices will provide 3 hours of violet light exposure each day at an intensity approximately equivalent to normal average outdoor exposure to prevent or slow myopia progression.
Features:
- 3 hours of VL exposure equivalent to outdoor exposure
- Attachable to any pair of standard children’s glasses
- Minimizes increase risk of infection or systemic side effects associated with other therapies
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Professional Services
Introducing the VS 2020
Self Guided Entrance Exams, Anywhere Anytime
The VS2020 is a virtual reality platform engineered to enhance patient engagement, reduce staff involvement, and deliver objective measurements.. With our unique self-guided technology, patients can independently complete seven common entrance tests from any location within your practice.
Test results are uploaded to a secure provider portal and can be evaluated from any device on your network. Embrace the future of eye care with the VS2020 platform!
7 Entrance Exams in one platform
Pupil response ● Eye motility ● Eye alignment, alternative cover test ● Eye alignment, unilateral cover/ uncover ● Color vision ● Contrast sensitivity ● Screening visual fields
TrueTrac gaze based navigation
The first Hands-free VR based testing experience. Helps standardize the exam process, while minimizing false click errors.
Dynamic Viewing / Reporting
Manage the testing process from any connected device on your network, With dynamic reporting, results can be analyzed for changes over time, giving you deeper insights into your patients’ eye health.
Kali Care
Glaucoma Precision Care
Kali Home
Transforming Glaucoma Management with At-Home Eye Pressure Monitoring
Infrequent IOP (intraocular pressure) measurements can limit glaucoma management, but Kali Home aims to change that.
This take-home device will enable patients to self-monitor their eye pressure, enhancing disease tracking and providing data for more personalized glaucoma care.
Kali Home* will offer:
- LED-based guidance assistance for effortless self-alignment
- Automatic measurement capture
- Bluetooth connectivity with our mobile app for trend analysis and seamless communication with the patient’s eye care professional
- Integrates into our Twenty/Twenty Vision Suite for comprehensive glaucoma management
Stay tuned for the Kali Home revolution in glaucoma management!
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Kali Smart Dropper
Enhancing Eye Drop Adherence with Innovative Technology
Applying and tracking eye drop medication can be challenging, but the Kali Smart Dropper aims to change that. This smart eye dropper assistant will help boost adherence by reminding patients to take their drops, confirming they were applied correctly, and assisting with data collection and reporting.
The Kali Smart Dropper* will be a lightweight, portable,device designed to attach to an eye drop bottle. As a connected smart eye dropper, it will provide drop instillation assistance and real-time tracking of successful drop use.
Features of the Kali Smart Dropper* will include:
- Guidance feedback during drop application
- Detection of successful drop installation
- Adherence tracking and reminders via our mobile app
- Integrates into our Twenty/Twenty Vision Suite for comprehensive glaucoma management
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Tonoptic
Continuous IOP Monitoring: A Breakthrough in Glaucoma Management
Eye pressure tends to be most elevated in the early morning when patients are asleep. These unmonitored early morning spikes can negatively affect glaucoma management. While home monitoring devices are helpful, their effectiveness depends on users taking the initiative to take a measurement.
Tonoptic is a minimally invasive, implantable device created to offer continuous eye pressure monitoring, enabling personalized and precise glaucoma management.
Utilizing advanced microelectronics, Tonoptic will feature an optically integrated MEMS pressure sensor and a handheld reader. The device will integrate with the Twenty/Twenty Vision Suite for comprehensive glaucoma management.
Tonoptic is set to revolutionize glaucoma care.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Dry Eye Therapeutics
Viscous Microdose Delivery
Simplifying Eye Drop Instillation
Applying eye drops correctly can be challenging due to aiming difficulties, blinking or flinching and dexterity issues
Our aim is to make eye drop application easier, while reducing waste. This innovative device automatically releases a microdose of the selected eye drop onto the ocular surface (not the eyelids) using a unique LED aiming technique, triggered right after the user blinks!
This product will come with interchangeable cartridges of ophthalmic eye drops, starting with lubricating artificial tears to help manage dry eye symptoms.
Key features will include:
- Horizontal eye drop delivery
- LED-guided aiming for precise drop placement
- Automatic blink delivery and a manual delivery option
- Connectivity with our mobile app for eye drop and symptom tracking, as well as adherence reminders
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Learn MoreKali Care
Meibomian Gland Dysfunction
Transforming MGD Therapy: Combining Heat and Massage in One Simple Solution
Dry eye caused by meibomian gland dysfunction (MGD) can be painful and costly to manage, with current treatments presenting various challenges.
At-home therapies like compress masks often fall short and require extra time and maintenance, while in-office procedures are expensive, complex, and lengthy.
Our solution will combine the typical in-office procedure into a single device, applying therapeutic levels of heat to the eyelids and delivering targeted massage to the entire lid in under 3 minutes, streamlining MGD treatment for patients.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Aqueous Deficiency
Natural Dry Eye Relief
Dry-eye disease can be painful, expensive, and challenging to manage, significantly impacting patients’ quality of life and comfort.
Our innovative solution is an ocular wearable device, similar to a contact lens, but discreetly located in the inferior fornix (hidden by the lower eyelid). This unique device uses low-level electrical currents to stimulate natural tear production for those with dry eye, all while being encased in a comfortable hydrogel material.
- Natural, preservative free dry eye therapy
- Wireless, on-demand therapy initiation for all day relief
- Integrates into Twenty/Twenty Vision Suite for comprehensive dry eye management
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Smart Lenses
Drug Dispensing Contact Lens
Simplifying Therapy Adherence for Glaucoma
Managing glaucoma can be challenging, especially when it comes to medication adherence at home.
Our solution is a programmable drug dispensing contact lens designed to improve compliance of vision-saving glaucoma medications.
- Controls timing and dose of drug delivery
- Improves medication compliance
- Reduces eye drop intolerance by minimizing dose
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Neuroprotection
Fighting Blindness with Groundbreaking Neuroprotection Lenses
Retinitis Pigmentosa (RP) is a rare inherited disease that often results in blindness and currently, no definitive treatment is available.
Our Neuroprotection Lens offers hope by aiming to slow or halt retinal degeneration in RP patients and other neurodegenerative eye diseases through transcorneal stimulation.
This product will utilize transcorneal stimulation to reverse retinal degeneration in patients with RP and other degenerative eye diseases.
- Clinical data supports neuro-protective and vision enhancing efficacy
- Well-tolerated, non-invasive therapy
Tackling the challenges of degenerative eye disease with our revolutionary Neuroprotection Lens.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Horizon
Closed-loop Glaucoma Pump
Revolutionizing Glaucoma Treatment
Glaucoma drainage devices often fail in a significant number of patients, with nearly 50% of implants becoming ineffective after just one year.
Our device is a closed-loop glaucoma pump designed to revolutionize glaucoma treatment. It is the first active glaucoma drainage device that will dynamically regulate intraocular pressure for more consistent eye pressure management in patients with glaucoma.
Expected Benefits:
- Overcomes common reasons for failure of glaucoma drainage implants
- Dynamic IOP control in both the diurnal cycle and over time
- Anti-immunogenic material to reduce post-implantation fibrosis
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Intravitreal Injection
Personalizing IVI therapy
Intravitreal injection (IVI) therapy is widely used for nvAMD and DR, but over 10% of patients don’t adquently respond and undergo multiple cycles before changing therapy, risking vision loss. Biomarkers could help physicians personalize treatment for individual patients.
Our advanced intravitreal injection technology allows for tissue sampling and therapeutic injection in one step, analyzing vitreous biomarkers to determine the best treatment options for macular degeneration patients.
Anticipated Benefits:
- Personalized therapy based on biomarkers
- Reduced risk of IVI complications
- Eliminates current “trial and error” approach for macular degeneration therapy
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
Myopia Wearables
Combating Myopia with Violet Light Technology
Myopia is a growing pandemic with highest rates in Asia. Current solutions are expensive, time consuming, increase risk of infection or have potential for side effects (Ortho-K, soft Multifocal contact lenses, Atropine).
Myopia wearable is a pair of compact optoelectronic components that can be semipermanently attached to a child’s glasses of choice to emit violet light that has been shown to slow myopia progression. The devices will provide 3 hours of violet light exposure each day at an intensity approximately equivalent to normal average outdoor exposure to prevent or slow myopia progression.
Features:
- 3 hours of VL exposure equivalent to outdoor exposure
- Attachable to any pair of standard children’s glasses
- Minimizes increase risk of infection or systemic side effects associated with other therapies
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
*Note: These products in development have not been evaluated by FDA, and are not available for sale in the United States.
MKT-01001 Rev A